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Clinicians should also monitor nutritional risks associated with rapid weight loss, such as deficiencies in iron, folic acid, and B vitamins, to ensure the patient is pregnancy-ready rather than just weight-ready. Given that GLP-1RAs improving IVF outcomes remains limited, their appropriate positioning remains a metabolic optimization tool before ART rather than a standardized pretreatment regimen ( 7 From evidence to decision: estimating net benefit under uncertainty Clinical decisions around GLP-1RAs in fertility-focused PCOS care are rarely binary

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The most successful approach combines consistent timing, regular meal tracking, and ongoing communication with your PlexusDx provider about appetite, energy, and weight trends

it is only available through approved clinical trials and is not accessible via the NHS